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Drug Discovery


Blood Cancer Drug Discoveries

What the Future Holds

Publication Date   April 2008
Publisher   Espicom
Product Type   Report
Pages   245
ISBN Number   978-1-85822-314-8
Product Code   ESP01068
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Summary


This New Strategic Report from Espicom Provides A Comprehensive Review of Current and Future Treatments for Major Blood Cancer Therapy Areas: Chronic Lymphocytic Leukaemia, Chronic Myeloid Leukaemia, Acute Myeloid Leukaemia, Multiple Myeloma and Non-Hodgkin's Lymphoma.

Over 275 Pages of Product Analysis, Market Statistics and Forecasts Unique Market Share and 5-Year Sales Forecasts for Leading Products & Pipeline Prospects A Comprehensive Examination of Major Blood Cancer Therapy Areas Critical Competitive Evaluation and Scoring of Current and Future Products.

Providing...

  • Detailed Analysis and 5-Year Forecasts for Current Leading Products by Value
  • A Detailed Review and Assessment of up and Coming Products
  • Unique Product Assessment and Scoring
  • An Evaluation of The Current Understanding of Blood Cancers

Major Areas Covered

  • Chronic Lymphocytic Leukaemia
  • Chronic Myeloid Leukaemia
  • Acute Myeloid Leukaemia
  • Multiple Myeloma
  • Non-Hodgkin's Lymphoma

The Report Covers Major Blood Cancer Areas

  • Chronic Lymphocytic Leukaemia
  • Chronic Myeloid Leukaemia
  • Acute Myeloid Leukaemia
  • Multiple Myeloma
  • Non-Hodgkin's Lymphoma

The Market

  • Risk Factors, How The Disease Affects Patients, Diagnosis and Stages of The Disease
  • The Market in 2007 and 2012
  • Growth Drivers and Dampeners

Patient Statistics

  • Prevalence
  • Diagnosis Rates
  • Unmet Clinical Need

Current Treatment Options

  • Interventions by Type
  • Unique Five Point Competitive Assessment and Scoring of Current Therapies and Companies Involved
  • 5-Year Sales Forecasts for Key Products

R&d: Drugs in Late Stage Development

  • Focus on New Classes of Drugs and The Companies Involved
  • Unique Competitive Assessment and Scoring of New Therapies and Companies Involved
  • 5-Year Sales Forecasts for Key Products from Year of Launch

Extensive Tables and Charts

Content


  • Blood Cancers
    • US Incidence of Blood Cancers, 2007
  • Unmet Medical Need
  • New Agents in Development
    • New Mechanisms of Action under Investigation for The Development of Blood Cancers:
    • Monoclonal Antibodies in Development for Treatment of Blood Cancers
  • Major Players
    • 2007
    • Market Share of Players in The Worldwide Blood Cancers Market, 2007
    • 2012
    • Market Share of Players in The Worldwide Blood Cancers Market, 2012
  • Global Sales
    • Estimated and Forecast Worldwide Sales in The Treatment of Blood Cancers (US$ Millions)
    • Regional Breakdown of Blood Cancer Market by Sales - 2007 and 2012
  • Chronic Lymphocytic Leukaemia
  • Background
  • Patient Statistics
    • Patient Model
    • Estimated Prevalence of Cll in Major Markets, 2005-2012
  • Drug Growth Drivers
  • Drug Growth Dampeners
  • The Market
    • Global Market
    • Forecast Cll Market Growth (US$ Millions)
    • Major Players
    • Current Drugs Commonly Used in The Treatment of Cll
    • Major Players in Cll by Sales - 2007
    • Forecast Major Players in Cll by Sales - 2012
  • The Drugs
  • Current Drugs
    • Selected Response Rates from Studies of First Line Treatment of Cll:
  • Fludara
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Fludara Sales in Cll by Region (US$ Millions)
    • Forecast Fludara Sales in Cll by Use (US$ Millions)
    • Competitor Ratio Analysis
  • Rituxan
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Blood Cancer Drug Discoveries: What The Future Holds
    • Sales Forecasts and Assumptions
    • Forecast Rituxan Sales in Cll by Use (US$ Millions)
    • Forecast Rituxan Sales in Cll by Region (US$ Millions)
    • Competitor Ratio Analysis
  • Campath
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Campath Sales in Cll by Use (US$ Millions)
    • Competitor Ratio Analysis
  • Agents in Development
    • Drugs in Development for The Treatment of Cll
    • Agents in Late Stage Development for Cll:
  • Treanda
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Treanda Sales in Cll (US$ Millions)
    • Competitor Ratio Analysis
  • Genasense
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Genasense in Cll Efficacy Summary:
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Genasense Sales in Cll by Region (US$ Millions):
    • Forecast Genasense Sales in Cll by Use (US$ Millions):
    • Competitor Ratio Analysis
  • Ofatumumab
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Ofatumumab Sales in Cll by Region (US$Millions):
    • Forecast Ofatumumab Sales in Cll by Use (US$Millions):
    • Competitor Ratio Analysis
  • Alvocidib
    • Blood Cancer Drug Discoveries: What The Future Holds
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Alvocidib Sales in Cll (US$ Millions)
    • Competitor Ratio Analysis
  • Lumliximab
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Lumiliximab Sales in Cll (US$ Millions)
    • Competitor Ratio Analysis
  • Revlimid
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Revlimid Cll Sales by Use (US$ Millions):
    • Forecast Revlimid Cll Sales by Region (US$ Millions):
    • Competitor Ratio Analysis
  • Chronic Myeloid Leukaemia
  • Background
  • Patient Statistics
    • Trends in US Cml Incidence:
    • Estimated Incidence in Worldwide Cml Prevalence:
  • Drug Growth Drivers
  • Drug Growth Dampeners
  • The Market
    • Global Market
    • Forecast Worldwide Cml Market (US$ Millions)
    • Major Players - 2007
    • Major Players in Cml by Sales - 2007
    • Major Players - 2012
    • Forecast Major Players in Cll by Sales - 2012
  • The Drugs
    • Cml Treatment Timeline:
    • Current Drugs
    • Current Drugs Used in The Treatment of Cml:
  • Gleevec/Glivec
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Blood Cancer Drug Discoveries: What The Future Holds
    • Iris Study: 18-Month Response Rates Determined by Intent-to-Treat Analysis
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Gleevec Sales in Cml (US$ Millions) - Excludes Sales in Gist
    • Competitor Ratio Analysis
  • Sprycel
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Sprycel Cml Sales (US$ Millions):
    • Competitor Ratio Analysis
  • Tasigna
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Tasigna Cml Sales Forecast (US$ Millions)
    • Competitor Ratio Analysis
  • Agents in Development
    • Drugs in Development for The Treatment of Cml:
    • Agents in Late Stage Development for Cml:
  • Bosutinib
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Bosutinib Sales in Cml (US$ Millions)
    • Competitor Ratio Analysis
  • Panobinostat
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Competitor Ratio Analysis
  • Mk-0457/ Vx 680
    • Blood Cancer Drug Discoveries: What The Future Holds
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Competitor Ratio Analysis
  • Acute Myeloid Leukaemia
  • Background
    • French-American-British (Fab) Classification of Aml
    • Who Aml Classification:
    • Selected Risk Factors Associated with Aml:
    • Common Chromosomal Abnormalities in Aml:
  • Patient Statistics
    • Forecast Incidence of Aml by Region:
  • Drug Growth Drivers
  • Drug Growth Dampeners
  • The Market
    • Global Market
    • Forecast Worldwide Adult Aml Market
    • Major Players - 2007
    • Major Players - 2012
    • Forecast Major Players in Aml by Sales - 2012
  • The Drugs
    • Treatment Nave Patients
    • Relapsed & Refractory Aml
    • Current Drugs Used in The Treatment of Aml:
    • Therapeutic Strategies in Aml and Relapsed/Refractory Aml:
  • Mylotarg
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Summary of Response Rates in Mylotarg Studies:
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Competitor Ratio Analysis
  • Agents in Development
    • Agents in Late Stage Development for Aml:
  • Clolar/Evoltra
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Sales of Clolar/Evoltra in Adult Aml (US$ Millions):
    • Competitor Ratio Analysis
    • Blood Cancer Drug Discoveries: What The Future Holds
  • Cloretazine
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Sales of Cloretazine in Aml (US$ Millions)
    • Competitor Ratio Analysis
  • Zarnestra
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Competitor Ratio Analysis
  • Dacogen
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Dacogen Sales in Adult Aml (US$ Millions)
    • Competitor Ratio Analysis
  • Lestaurtinib
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Lestaurtinib Sales in Aml (US$ Millions)
    • Competitor Ratio Analysis
  • Midostaurin
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Midostaurin Sales in Aml (US$ Millions)
    • Competitor Ratio Analysis
  • Tandutinib
    • Novelty/Rationale for Mechanism of Action
    • Blood Cancer Drug Discoveries: What The Future Holds
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Competitor Ratio Analysis
  • Zosuquidar
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Competitor Ratio Analysis
  • Xanafide
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Xanafide Sales in Aml (US$ Millions)
    • Competitor Ratio Analysis
  • Ceplene
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Ceplene Sales in Aml (US$ Millions)
    • Competitor Ratio Analysis
  • Multiple Myeloma
  • Background
  • Patient Statistics
    • Patient Model
    • Estimated Prevalence of Multiple Myeloma in Selected Markets
  • Drug Growth Drivers
  • Drug Growth Dampeners
  • The Market
    • Global Market
    • Forecast Worldwide Multiple Myeloma Market (US$ Millions):
    • Major Players
    • Major Players in Multiple Myeloma by Sales - 2007
    • Major Players in Multiple Myeloma by Sales - 2012
    • Current Drugs Used in The Treatment of Multiple Myeloma:
  • The Drugs
    • Blood Cancer Drug Discoveries: What The Future Holds
  • Thalomid
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Thalomid Sales in Multiple Myeloma (US$ Millions)
    • Competitor Ratio Analysis
  • Revlimid
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Data Summary of Mm-009 and Mm - 010 Studies:
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Front Line Myeloma Comparison:
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Competitor Ratio Analysis
  • Velcade
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Velcade Sales in Multiple Myeloma (US$ Millions)
    • Competitor Ratio Analysis
  • Agents in Development
    • Drugs in Development for The Treatment of Multiple Myeloma:
    • Agents in Late Stage Development for Multiple Myeloma:
  • Tanespimycin
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Tanespimycin Sales in Relapsed/Refractory Multiple Myeloma (US$ Millions)
    • Competitor Ratio Analysis
  • Mapatumumab
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Blood Cancer Drug Discoveries: What The Future Holds
    • Sales Forecasts and Assumptions
    • Competitor Ratio Analysis
  • Belinostat
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Competitor Ratio Analysis
  • Perifosine
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Competitor Ratio Analysis
  • Carfilzomib
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Competitor Ratio Analysis
  • Non Hodgkin's Lymphoma
  • Background
    • Frequency of Nhl Subtypes in Adults:
    • 1) B-Cell Cll/Small Lymphocytic Lymphoma
    • 2) Marginal Zone Lymphoma
    • 3) Lymphoplasmocytic Lymphoma (Waldenstrom Macroglobulinemia):
    • 4) Follicular Lymphoma:
    • 1) Cutaneous T-Cell Lymphoma:
    • 1) Diffuse Large B-Cell Lymphoma (Dlbcl):
    • 2) Mantle Cell Lymphoma:
    • 3) Burkitt Lymphoma/Burkitt-like Lymphoma:
    • 4) Precursor B-Cell Leukaemia/Lymphoma
    • 1) Anaplastic Large T/Null-Cell Lymphoma:
    • 2) Precursor T-Lymphoblastic Lymphoma/Leukaemia:
    • 3) Peripheral T-Cell Lymphomas:
  • Staging Systems
  • Patient Statistics
    • Patient Model
    • Forecast Nhl Incidence and Prevalence (000s)
  • Drug Growth Drivers
  • Drug Growth Dampeners
  • The Market
    • Blood Cancer Drug Discoveries: What The Future Holds
    • Global Market
    • Forecast Nhl Market (Excluding Ctcl) - US$ Millions
    • Forecast Ctcl Market - US$ Millions
    • Major Players
    • Current Drugs Commonly Used in The Treatment of Nhl
    • Major Players in Nhl by Sales - 2007
    • Major Players in Nhl by Sales - 2012
  • The Drugs
    • Low Grade or Indolent Nhl
    • Treatment Options in Indolent/Low-Grade Nhl:
    • Intermediate- and High-Grade Lymphomas:
    • T-Cell Lymphomas:
    • Summary of Common Therapies in Nhl
  • Marketed Agents for Use in Nhl
  • Rituxan
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Rituxan Penetration Rates, Q3-Q4 2005
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Rituxan Sales in Nhl Indications by Region (US$ Millions)
    • Forecast Rituxan Sales in Nhl Indications by Use (US$ Millions)
    • Competitor Ratio Analysis
  • Fludara
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Fludara Sales in Nhl Indications (US$ Millions)
    • Competitor Ratio Analysis
  • Bexxar
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Bexxar Sales (US$ Millions):
    • Competitor Ratio Analysis
  • Zevalin
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Blood Cancer Drug Discoveries: What The Future Holds
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Zevalin Sales (US$ Millions)
    • Competitor Ratio Analysis
  • Marketed Agents for Cutatenous T-Cell Lymphoma
  • Zolinza
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Zolinza Sales in Ctcl (US$ Millions)
    • Competitor Ratio Analysis
  • Agents in Development
    • Drugs in Development for The Treatment of Nhl:
    • Agents in Late Stage Development for Nhl:
  • Treanda
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Treanda US Sales Forecasts in Nhl Indication (US$ Millions)
    • Competitor Ratio Analysis
  • Ofatumumab
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Phase I/Ii Trial Results Summary:
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Sales of Ofatumumab in Nhl by Region (US$ Millions):
    • Forecast Sales of Ofatumumab in Nhl by Use (US$ Millions):
    • Competitor Ratio Analysis
  • Galiximab
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Galiximab Sales in Nhl (US$ Millions)
    • Competitor Ratio Analysis
    • Blood Cancer Drug Discoveries: What The Future Holds
  • Pixantrone
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Pixantrone Nhl Sales by Region (US$ Millions):
    • Forecast Pixantrone Sales in Nhl by Use (US$ Millions)
    • Competitor Ratio Analysis
  • Revlimid
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Revlimid Sales Forecasts in Nhl (US$ Millions)
    • Competitor Ratio Analysis
  • Torisel
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Torisel Sales in Mcl (US$ Millions)
    • Competitor Ratio Analysis
  • Velcade
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Velcade Sales in Mcl (US$ Millions)
    • Forecast Velcade Sales in Follicular Nhl (Excludes Mcl) by Region (US$ Millions)
    • Forecast Velcade Sales in Follicular Nhl (Excludes Mcl) by Use (US$ Millions)
    • Competitor Ratio Analysis
  • Inotuzumab Ozogamicin
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Blood Cancer Drug Discoveries: What The Future Holds
    • Competitor Ratio Analysis
  • Agents in Late Stage Development for Cutaneous T-Cell Lymphoma
  • Zanliumumab
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Sales of Zanolimumab in Ctcl (US$ Millions)
    • Competitor Ratio Analysis
  • Belinostat
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Sales of Belinostat in Ctcl (US$ Millions)
    • Competitor Ratio Analysis
  • Fodosine
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Forecast Sales of Fodosine in Ctcl (US$ Millions)
    • Competitor Ratio Analysis
  • Epratuzumab
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Competitor Ratio Analysis
  • Enzastaurin
    • Novelty/Rationale for Mechanism of Action
    • Proof of Concept/Clinical Data
    • Management/Clinical Expertise
    • Competition within The Marketplace/Gaining Share of Voice
    • Risks Associated with Developing A Drug within A Therapeutic Class
    • Filings and Approval
    • Sales Forecasts and Assumptions
    • Competitor Ratio Analysis
  • Cra Analysis: Aml
    • Blood Cancer Drug Discoveries: What The Future Holds
    • Cra Summary
  • Cra Analysis: Cml
    • Cra Summary
  • Cra Analysis: Cll
  • Cra Analysis: Multiple Myeloma
    • Cra Summary
  • Cra Analysis: Nhl
    • Cra Analysis - Nhl
    • Cra Analysis - Nhl (Continued)...includes Ctcl
  • Acronyms